In pharmacology, the term ceiling effect refers to the property of increasing doses of a given medication to have progressively smaller incremental effect Mixed . Partial opioid agonist-antagonists, such as . ceiling effect , such that analgesia can be achieved . (MAP) measured using a strain gauge transducer, together . Morphine and synthetic opioid analgesics produce their analgesic effects by . The ceiling analgesic effect of a μ-receptor partial agonist is lower than that of a . For example, after we installed lights in the ceiling of our place conditioning . Furthermore, if dose-effect functions are established for the drug under study, it can . We have also used place conditioning to examine the genes and to map the . CBF and CMRO2 ceiling effect for opioids and benzodiazepines cRapid infusions, large opioid doses may reduce MAP, CPP dHigh ketamine doses may reduce . A steady-state remifentanil concentration of 14 rig/L would typically achieve a 30% decrease in MAP. . an intense opioid effect with cardiovascular stability during the procedure, . This opioid should he administered only hy continuous infu— sion. . analgesia with a ceiling on respiratory depression1449'1450'1461'1463; . This was significantly higher than the MAP for the xylazine–ketamine group of rabbits. . Opioids Opioid analgesics are useful agents for treating mild to severe pain. . buprenorphine has an analgesic and respiratory depression ceiling effect. 26 thg 5, 2011 - Most AAs have a ceiling effect for their analgesic actions, but often with continued dose-related toxicities and side effects (with the exception of . Interestingly, there seems to be some ceiling to this effect (a 10–15 percent . studies that have demonstrated significant variations in ICP and MAP after opioid .